The Power Fantasy - an alternate take on life sharing a world with beings capable of terrifying levels of destruction. The first issue has a telepath wipe out scores of WH staff from the President down as a conciliatory measure to calm down another superpowered guy from destroying an entire state in retaliation for an assassination attempt. It just gets wilder from there, including a magical pyramid scheme, an angel, and an artist whose mood swings can summon Godzilla* if she gets too upset, which makes meeting art critics a delight, and has her girlfriend treading very lightly 24:7.
* Actually, the way everyone is in abject terror of her losing composure, I get the feeling it may actually be more like Cthulhu, or The Void