If we are playing Mattel predictions, I'm going to guess mainstream all the way. At least for the start. More Batman, more Superman, all the core DC characters that you and I are thinking of, the stuff we already have multiple times over. All of this has to sell through first, then they MIGHT start to think more niche, MIGHT start to get artist-specific, MIGHT start doing figures from 30 year old movies (they did MOTU movie), but that's going to be years out if ever. I'm guessing more cookie-cutter than unique sculpt. It might look alright, who knows, we'll have to wait and see.
Like I say, I'm holding out hope for Shreck. Even if GameStop, Target, and Walmart don't work out, I try to network here and other places and at times that proves successful. Worst case, if I don't get him, I'm still excited for the Bat, the Cat, and the Penguin.